Endoscopy and biopsy

Flexible endoscopy is one of the world’s most common examination methods. It involves inserting a flexible, tube-like camera instrument into the body’s natural openings to investigate the cause of the patient’s problems. The endoscope has strong illumination, a camera for still images and video, as well as a channel for flexible biopsy instruments that enable sampling of suspected tumour tissue.

During the examination, tissue samples (biopsies) are taken from the organs and from any suspicious changes that are discovered. The samples are then sent for analysis to determine whether there is cancer or signs of disease (e.g. infection). The quality of the (biopsy) sample is crucial in order to determine whether the patient is suffering from cancer and, if so, what type exactly. If the quality of the sample is poor, re-examination might be required, and more complicated and risky methods may be considered. Flexible endoscopy became popular in clinical practice in the 1970s, and has since revolutionised the diagnosis and treatment of cancer. The organs most commonly examined by means of flexible endoscope are the stomach, the intestines and the respiratory tract. BiBB develops flexible disposable instruments for sampling of these organs. The EndoDrill® instruments are inserted through the flexible channel of the endoscope, and are compatible with all standard endoscopes on the market. For the diagnosis of tumours in the breast and other forms of tumours, for example liver and prostate, no endoscope is required. For these applications, BiBB offers rigid and shorter core needle instruments.

Today’s biopsy instruments are disposable products in the form of needles and small forceps. The doctor (endoscopist) collects a number of biopsies via the endoscope. These are then sent to the pathology lab for analysis. At pace with the growth of modern individualised treatment of various forms of tumours, increasing demands are being placed for accurate diagnosis prior to the start of treatment. It is clear that the weak link at the moment is the tissue samples (biopsies) required for complete diagnosis on which treatment can be based. Existing biopsy instruments have not kept up with the rapid development and do not collect biopsies of high enough quality. It is here that BiBB meets an important clinical need with its EndoDrill® technology, which offers deep-penetrating functionality and precision.