– Case study
EndoDrill® in clinical use
A 79 year old male was referred for gastroscopy due to anemia. The endoscopy revealed a submucous tumor along the greater curvature in the distal stomach. 6 consecutive biopsies were harvested, 3 with the conventional forceps and 3 with the EndoDrill® instrument in a randomized clinical study stratified for order and location of the biopsies. One of the EndoDrill® biopsies showed a GIST but none of the 3 samples harvested with the forceps were diagnostic. The patient had the 2,5 cm large tumor resected laparoscopically. Histology showed a radically excised GIST, group II (low risk) according to Miettinen and Lasota. The postoperative period was uneventful.
Sampling of submucosal lesions in the gastrointestinal tract through a flexible endoscope is a well-recognized clinical problem. Biopsies provided by the forceps are usually epithelial only and sufficient amount of representative submucosal material is seldom achieved. Consequently most tumors larger than two centimetres are surgically resected without a preoperative diagnosis. For smaller tumours, < 2 centimetres, establishing a tissue diagnosis are of utmost importance not only for the single patient but also for decreasing the work load of endoscopic follow-ups. Our invention should be seen as the first attempt to accomplish this.